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Secondary endpoints included the proportion of participants achieving 5% and 10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and -cell function

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Because this general schema of NO function is long established and broadly accepted, I will focus less on NOs status as a bona fide co-transmitter than for other metabolites discussed in this review

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